Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 15/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920801 | 0.74 | ESR2 (0.33) | KDM1AKCNH2KDM1B | |
| SCHEMBL13262730 | 0.67 | ESR2 (0.47) | — | |
| SCHEMBL8217508 | 0.66 | ESR2 (0.49) | — | |
| SCHEMBL14790104 | 0.65 | HTR2A (0.55) | KDM1AKCNH2KDM1BHTR2AHTR2C | |
| SCHEMBL19720190 | 0.65 | KDM1A (0.58) | KDM1AKCNH2KDM1BMAOB | |
| SCHEMBL16482910 | 0.64 | — | — | |
| SCHEMBL7733239 | 0.64 | ESR2 (0.32) | — | |
| SCHEMBL10014263 | 0.63 | ESR2 (0.43) | — | |
| SCHEMBL16961834 | 0.63 | — | — | |
| SCHEMBL20475345 | 0.62 | PDE4A (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |