Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15203316 | 0.87 | — | — | |
| SCHEMBL78985 | 0.87 | — | — | |
| SCHEMBL5080110 | 0.87 | — | — | |
| SCHEMBL3123535 | 0.84 | — | — | |
| Hexane SCHEMBL9392301 | 0.81 | TSHR (0.50) | TSHRTHRBSLC22A1SLC22A2OPRM1 | |
| SCHEMBL7875891 | 0.80 | — | — | |
| SCHEMBL13524037 | 0.78 | ACE2 (0.48) | TSHRALDH1A1THRBSLC22A1OPRM1 | |
| SCHEMBL31187957 | 0.78 | ACE2 (0.48) | TSHRALDH1A1THRBSLC22A1OPRM1 | |
| SCHEMBL22986828 | 0.78 | ACE2 (0.48) | TSHRALDH1A1THRBSLC22A1OPRM1 | |
| SCHEMBL31187914 | 0.78 | ACE2 (0.48) | TSHRALDH1A1THRBSLC22A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707588-A4 | IMPROVED ALKYLLITHIUM PROCESS | FMC CORP (US) | 1999-06-09 | — | — | EP | disclosed |
| EP-0707588-A1 | IMPROVED ALKYLLITHIUM PROCESS | FMC CORPORATION (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001982-A1 | IMPROVED ALKYLLITHIUM PROCESS | FMC CORPORATION (US) | 1995-01-19 | — | — | WO | disclosed |
| US-5332533-A | Reacting alkyl halide with lithium metal particles in a liquid hydrocarbon solvent | FMC CORPORATION (US) | 1994-07-26 | — | — | US | disclosed |