Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30466713 | 0.81 | AOC3 (0.52) | AOC3LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL411887 | 0.79 | AOC3 (0.59) | AOC3LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL26025745 | 0.79 | AOC3 (0.59) | AOC3LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL9577935 | 0.77 | AOC3 (0.57) | AOC3LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL10772333 | 0.74 | AOC3 (0.46) | AOC3LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL10451736 | 0.73 | AOC3 (0.53) | AOC3LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL112589 | 0.73 | AOC3 (0.57) | AOC3LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL9334567 | 0.73 | AOC3 (0.57) | AOC3LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL477440 | 0.73 | AOC3 (0.57) | AOC3LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL6464699 | 0.73 | AOC3 (0.57) | AOC3LMNAADRA2AADRA2CHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856492-A | N-HYDROXYHYDROCARBYL-N-HETEROCYCLE, REVERSE TRANSCRIPTASE INHIBITOR INTERMEDIATE | MERCK & CO., INC. (US) | 1999-01-05 | — | — | US | disclosed |