SCHEMBL8330749

SCHEMBL8330749

O=COCc1cc2cccc3ccc4cccc1c4c32

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.43
ERBB2 P04626 1/20 0.43
FYN P06241 1/20 0.43
MAOA P21397 1/20 0.43
ACHE P22303 1/20 0.43
AHR P35869 1/20 0.43
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
ALDH1A1 P00352 6/20 0.38
HPGD P15428 5/20 0.38
HSD17B10 Q99714 4/20 0.38
THRB P10828 1/20 0.38
CYP3A4 P08684 2/20 0.35
TSHR P16473 2/20 0.35
CYP1A1 P04798 2/20 0.35
CYP1B1 Q16678 2/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67895 0.87 KMT2A (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL27976524 0.79 PPARG (0.43) CYP1A2KMT2AMEN1ALDH1A1HPGD
SCHEMBL15327502 0.78 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL16328992 0.78 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL27705873 0.75 CYP1A2 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL975510 0.75 CYP1A2 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL12338012 0.75 CYP1A2 (0.44) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL20157722 0.74 CYP1A2 (0.43) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL12085952 0.74 CYP1A2 (0.43) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL6929500 0.74 KMT2A (0.53) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998039348-A9 PHOTOCLEAVABLE PROTECTING GROUPS AND METHODS FOR THEIR USE 1999-02-18 WO claimed