Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 3/20 | 0.55 |
| ▸ | TDP2 | O95551 | 1/20 | 0.55 |
| ▸ | NGF | P01138 | 1/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032312 | 0.90 | MEN1 (0.55) | MEN1KMT2AMAPTRECQLTDP2 | |
| SCHEMBL8336544 | 0.85 | MAPT (0.51) | MEN1KMT2AMAPTRECQLTDP2 | |
| SCHEMBL9635901 | 0.83 | MEN1 (0.61) | MEN1KMT2AMAPTRECQLTDP2 | |
| Lumiflavin SCHEMBL6373617 | 0.78 | MEN1 (0.72) | MEN1KMT2AMAPTRECQLTDP2 | |
| SCHEMBL24238131 | 0.78 | MEN1 (0.55) | MEN1KMT2AMAPTRECQLTDP2 | |
| SCHEMBL29375611 | 0.78 | MEN1 (0.55) | MEN1KMT2AMAPTRECQLTDP2 | |
| Lumiflavin SCHEMBL29516802 | 0.77 | MEN1 (0.76) | MEN1KMT2AMAPTRECQLTDP2 | |
| SCHEMBL3476023 | 0.77 | GSR (0.65) | MEN1KMT2AMAPTRECQLTDP2 | |
| Lumiflavin SCHEMBL193713 | 0.77 | MEN1 (0.76) | MEN1KMT2AMAPTRECQLTDP2 | |
| Lumiflavin SCHEMBL6365933 | 0.76 | MEN1 (0.74) | MEN1KMT2AMAPTRECQLTDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925633-A | ADMINISTERING AS ANTIMETASTASIS AGENT | SYNPHAR LABORATIES, INC. (CA) | 1999-07-20 | — | — | US | disclosed |
| WO-1997032580-A1 | 3-SUBSTITUTED-4-OXA-1-AZABICYCLO[3,2,0]HEPTAN-7-ONE AS CYSTEINE PROTEASE INHIBITORS | SYNPHAR LABORATORIES INC. (US) | 1997-09-12 | — | — | WO | disclosed |