Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 1.00 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 6/20 | 1.00 |
| ▸ | HDAC2 | Q92769 | 6/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 1.00 |
| ▸ | HDAC4 | P56524 | 5/20 | 1.00 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 1.00 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 1.00 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 1.00 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 1.00 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 3/20 | 1.00 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pracinostat SCHEMBL29351549 | 1.00 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| Pracinostat SCHEMBL833105 | 1.00 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| Pracinostat SCHEMBL19554744 | 0.99 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| Pracinostat SCHEMBL19555095 | 0.99 | HDAC1 (0.98) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| Pracinostat SCHEMBL19555094 | 0.99 | HDAC1 (0.98) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| Pracinostat SCHEMBL19554745 | 0.99 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| Pracinostat SCHEMBL20984951 | 0.98 | HDAC1 (0.98) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| Pracinostat SCHEMBL19554778 | 0.98 | HDAC1 (0.98) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| Pracinostat SCHEMBL19554752 | 0.98 | HDAC1 (0.98) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| Pracinostat SCHEMBL19554751 | 0.98 | HDAC1 (0.98) | HDAC1HDAC8HDAC3HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230364089-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF PATHOLOGICAL CONDITIONS ASSOCIATED WITH EXCESS FIBRIN DEPOSITION AND/OR THROMBUS FORMATION | CERENO SCIENT AB (SE) | 2023-11-16 | — | — | US | claimed |
| US-11697674-B2 | Human chorionic gonadotropin variant peptides and treatment of breast cancer | INSTITUTE FOR CANCER RESEARCH (US) | 2023-07-11 | — | — | US | claimed |
| EP-3452035-B1 | POLYMORPHIC FORMS OF 3-[2-BUTYL-1-(2-DIETHYLAMINO-ETHYL)-1H-BENZOIMIDAZOL-5-YL]-N-HYDROXY-ACRYLAMIDE AND USES THEREOF | MEI PHARMA INC (US) | 2021-07-07 | — | — | EP | claimed |
| US-20210188935-A1 | HUMAN CHORIONIC GONADOTROPIN VARIANT PEPTIDES AND TREATMENT OF BREAST CANCER | INSTITUTE FOR CANCER RESEARCH D/B/A THE RESEARCH INSTITUTE OF FOX CHASE CANCER CENTER (US) | 2021-06-24 | — | — | US | claimed |
| US-10610570-B2 | Treating rotator cuff conditions | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2020-04-07 | — | — | US | claimed |
| EP-2131840-B1 | COMBINATION OF BENZIMIDAZOLE ANTI-CANCER AGENT AND A SECOND ANTI-CANCER AGENT | MEI PHARMA INC (US) | 2018-10-17 | — | — | EP | claimed |
| WO-2017175010-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF PATHOLOGICAL CONDITIONS ASSOCIATED WITH EXCESS FIBRIN DEPOSITION AND/OR THROMBUS FORMATION | CERENO SCIENTIFIC AB (SE) | 2017-10-12 | — | — | WO | claimed |
| US-9387263-B2 | RbAp48 transgenic mice for drug discovery in age-related memory decline | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-07-12 | — | — | US | claimed |
| US-20140294798-A1 | RbAp48 TRANSGENIC MICE FOR DRUG DISCOVERY IN AGE-RELATED MEMORY DECLINE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-10-02 | — | — | US | claimed |
| US-20140235649-A1 | USE OF PHOSPHATASE INHIBITORS OR HISTONE DEACETYLASE INHIBITORS TO TREAT DISEASES CHARACTERIZED BY LOSS OF PROTEIN FUNCTION | LIXTE BIOTECHNOLOGY, INC. (US) | 2014-08-21 | — | — | US | claimed |
| US-8143282-B2 | Heterocyclic compounds | S*BIO PTE LTD. (SG) | 2012-03-27 | — | — | US | claimed |
| EP-1937650-B1 | HETEROCYCLIC COMPOUNDS | S BIO PTE LTD (SG) | 2011-06-15 | — | — | EP | claimed |
| US-20100098691-A1 | COMBINATION OF BENZIMIDAZOLE ANTI-CANCER AGENT AND A SECOND ANTI-CANCER AGENT | S'BIO PTE LTD (SG) | 2010-04-22 | — | — | US | claimed |
| EP-2131840-A1 | COMBINATION OF BENZIMIDAZOLE ANTI-CANCER AGENT AND A SECOND ANTI-CANCER AGENT | S*Bio Pte Ltd (SG) | 2009-12-16 | — | — | EP | claimed |
| US-20090048300-A1 | Heterocyclic Compounds | S*BIO PTE LTD. (SG) | 2009-02-19 | — | — | US | claimed |
| WO-2008108741-A1 | COMBINATION OF BENZIMIDAZOLE ANTI-CANCER AGENT AND A SECOND ANTI-CANCER AGENT | S*BIO PTE LTD (SG) | 2008-09-12 | — | — | WO | claimed |
| EP-3664789-B1 | METHODS FOR TREATING DISEASES AND NERVE INJURY | CHILDRENS HOSPITAL MED CT (US) | 2023-11-22 | — | — | EP | disclosed |
| US-20230364089-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF PATHOLOGICAL CONDITIONS ASSOCIATED WITH EXCESS FIBRIN DEPOSITION AND/OR THROMBUS FORMATION | CERENO SCIENT AB (SE) | 2023-11-16 | — | — | US | disclosed |
| EP-1937650-A1 | HETEROCYCLIC COMPOUNDS | S*Bio Pte Ltd (SG) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007030080-A1 | HETEROCYCLIC COMPOUNDS | S*BIO PTE LTD (SG) | 2007-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230364089-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF PATHOLOGICAL CONDITIONS ASSOCIATED WITH EXCESS FIBRIN DEPOSITION AND/OR THROMBUS FORMATION | HDAC3, HDAC1, HDAC5 | HDAC1 2/4885HDAC8 9/4885HDAC3 1/4885 |
| US-20140235649-A1 | USE OF PHOSPHATASE INHIBITORS OR HISTONE DEACETYLASE INHIBITORS TO TREAT DISEASES CHARACTERIZED BY LOSS OF PROTEIN FUNCTION | HDAC1, PPP3CA, PPM1A | HDAC1 1/4885HDAC8 13/4885HDAC3 36/4885 |
| US-20090048300-A1 | Heterocyclic Compounds | HDAC1, HDAC3, HDAC11 | HDAC1 1/4885HDAC8 4/4885HDAC3 2/4885 |
| US-20100098691-A1 | COMBINATION OF BENZIMIDAZOLE ANTI-CANCER AGENT AND A SECOND ANTI-CANCER AGENT | PAICS, HDAC5, HDAC4 | HDAC1 47/4885HDAC8 7/4885HDAC3 29/4885 |
| US-10610570-B2 | Treating rotator cuff conditions | HDAC10, HDAC5, HDAC7 | HDAC1 4/4885HDAC8 7/4885HDAC3 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.