Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 4/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAG | P20916 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8332378 | 0.94 | POLB (0.46) | POLBSSTR5SSTR3SSTR4SSTR2 | |
| SCHEMBL8331347 | 0.92 | POLB (0.49) | POLBLMNAKMT2AL3MBTL1TP53 | |
| SCHEMBL11268177 | 0.91 | MAPK1 (0.53) | POLBLMNAKMT2AL3MBTL1MAG | |
| SCHEMBL11271837 | 0.90 | POLB (0.44) | POLBSSTR5SSTR3SSTR4SSTR2 | |
| SCHEMBL5840823 | 0.88 | SSTR5 (0.52) | POLBSSTR5SSTR3SSTR4SSTR2 | |
| SCHEMBL22053387 | 0.88 | SSTR5 (0.52) | POLBSSTR5SSTR3SSTR4SSTR2 | |
| SCHEMBL5840827 | 0.88 | SSTR5 (0.52) | POLBSSTR5SSTR3SSTR4SSTR2 | |
| SCHEMBL5841004 | 0.88 | SSTR5 (0.52) | POLBSSTR5SSTR3SSTR4SSTR2 | |
| SCHEMBL5840925 | 0.88 | SSTR5 (0.52) | POLBSSTR5SSTR3SSTR4SSTR2 | |
| SCHEMBL5841003 | 0.88 | SSTR5 (0.52) | POLBSSTR5SSTR3SSTR4SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3289078-A1 | CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS AUTOLYSIN E, METHOD OF PRODUCING THE CRYSTAL AND ITS USE IN SCREENING METHODS | J. Stefan Institute (SI) | 2018-03-07 | — | — | EP | disclosed |
| WO-2016173603-A1 | CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS AUTOLYSIN E, METHOD OF PRODUCING THE CRYSTAL AND ITS USE IN SCREENING METHODS | J. STEFAN INSTITUTE (SI) | 2016-11-03 | — | — | WO | disclosed |
| US-6008333-A | Preparation of glucosaminyl muramic acid derivatives | ENDOREX CORPORATION (US) | 1999-12-28 | — | — | US | disclosed |
| US-5750665-A | Preparation of glucosaminyl muramic acid derivatives | ENDOREX CORPORATION | 1998-05-12 | — | — | US | disclosed |