Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4798227 | 0.83 | HDAC4 (0.44) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL7046013 | 0.80 | HDAC4 (0.41) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL4804624 | 0.79 | HDAC4 (0.40) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL2996951 | 0.78 | HDAC4 (0.44) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL2992029 | 0.77 | HDAC4 (0.67) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL38661846 | 0.77 | HDAC4 (0.67) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL28319597 | 0.77 | HDAC4 (0.48) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL7702433 | 0.76 | HDAC4 (0.50) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL38665311 | 0.76 | HDAC4 (0.50) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL14491000 | 0.76 | HDAC4 (0.60) | HDAC4HDAC7HDAC5EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819119-A4 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN INC (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0819119-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN, INC. (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1997026245-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN, INC. (US) | 1997-07-24 | — | — | WO | disclosed |