Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717802 | 1.00 | ECE1 (0.43) | ECE1OPRM1OPRD1OPRK1PTGS1 | |
| SCHEMBL7464934 | 1.00 | ECE1 (0.43) | ECE1OPRM1OPRD1OPRK1PTGS1 | |
| SCHEMBL9228819 | 1.00 | ECE1 (0.43) | ECE1OPRM1OPRD1OPRK1PTGS1 | |
| SCHEMBL29592041 | 1.00 | ECE1 (0.43) | ECE1OPRM1OPRD1OPRK1PTGS1 | |
| SCHEMBL8717771 | 1.00 | ECE1 (0.43) | ECE1OPRM1OPRD1OPRK1PTGS1 | |
| SCHEMBL1443588 | 0.99 | ECE1 (0.44) | ECE1OPRM1OPRD1OPRK1PTGS1 | |
| SCHEMBL8710506 | 0.97 | ECE1 (0.43) | ECE1OPRM1OPRD1OPRK1PTGS1 | |
| SCHEMBL8397119 | 0.97 | ECE1 (0.45) | ECE1OPRM1OPRD1OPRK1PTGS1 | |
| SCHEMBL6136428 | 0.97 | ECE1 (0.45) | ECE1OPRM1OPRD1OPRK1PTGS1 | |
| SCHEMBL6129713 | 0.97 | ECE1 (0.45) | ECE1OPRM1OPRD1OPRK1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098526-A | Clostridium neurotoxin comprising exogenous activating ring | 益普生生物制药有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-112969797-A | Engineering strains of corynebacterium | 阿彻丹尼尔斯米德兰德公司 | 2021-06-15 | — | — | CN | disclosed |
| CN-112351992-A | Botulinum toxin cell binding domain polypeptides and methods for their use in skin regeneration | 阿勒根公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-112351991-A | Botulinum toxin cell binding domain polypeptides and methods for their use in treating fibrosis related disorders | 阿勒根公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-108822211-B | Method for preparing A, B, E, F type tetravalent botulinum antitoxin | 中国人民解放军军事科学院军事医学研究院 | 2019-12-24 | — | — | CN | disclosed |
| CN-108822211-A | A method of preparing A, B, E, F type tetravalence botulinum antitoxin | 中国人民解放军军事科学院军事医学研究院 | 2018-11-16 | — | — | CN | disclosed |
| CN-108619500-A | A kind of A, B, E, Botulinum toxin F tetravalent vaccine and preparation method thereof | 中国人民解放军军事科学院军事医学研究院 | 2018-10-09 | — | — | CN | disclosed |
| CN-100439394-C | Pharmaceutical use of secreted bacterial effector proteins | HEALTH AND NURSING AGENT CO (GB) | 2008-12-03 | — | — | CN | disclosed |
| CN-1531549-A | Pharmaceutical use of secreted bacterial effector proteins | 健康保护代理公司 | 2004-09-22 | — | — | CN | disclosed |
| EP-0842270-A4 | NUCLEIC ACID AND AMINO ACID SEQUENCES RELATING TO HELICOBACTER PYLORI FOR DIAGNOSTICS AND THERAPEUTICS | ASTRA AB (SE) | 1999-02-24 | — | — | EP | disclosed |
| CN-1186516-A | Nucleic acid and amino acid sequences relating to helicobacter pylori for diagnostics and therapeutics | ASTRA AB (SE) | 1998-07-01 | — | — | CN | disclosed |
| EP-0842270-A1 | NUCLEIC ACID AND AMINO ACID SEQUENCES RELATING TO HELICOBACTER PYLORI FOR DIAGNOSTICS AND THERAPEUTICS | AKTIEBOLAGET ASTRA (SE) | 1998-05-20 | — | — | EP | disclosed |
| WO-1996040893-A1 | NUCLEIC ACID AND AMINO ACID SEQUENCES RELATING TO HELICOBACTER PYLORI FOR DIAGNOSTICS AND THERAPEUTICS | ASTRA AKTIEBOLAG (SE) | 1996-12-19 | — | — | WO | disclosed |