Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.67 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.58 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.58 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.58 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.58 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.58 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17923073 | 0.84 | IDO1 (0.54) | IDO1NOTUMCYP3A4CYP2D6PSEN1 | |
| SCHEMBL16673120 | 0.84 | CYP3A4 (0.62) | IDO1NOTUMCYP3A4LMNAMAPT | |
| SCHEMBL710352 | 0.80 | IDO1 (1.00) | IDO1NOTUMCYP3A4CYP2D6PSEN1 | |
| SCHEMBL17923064 | 0.79 | IDO1 (0.49) | IDO1NOTUMCYP3A4CYP2D6PSEN1 | |
| SCHEMBL872661 | 0.78 | NOTUM (1.00) | IDO1NOTUMCYP3A4CYP2D6PSEN1 | |
| SCHEMBL17959123 | 0.77 | CYP17A1 (0.73) | IDO1NOTUMCYP3A4CYP2D6PSEN1 | |
| SCHEMBL17959125 | 0.77 | CYP17A1 (0.73) | IDO1NOTUMCYP3A4CYP2D6PSEN1 | |
| SCHEMBL13985219 | 0.74 | MAPT (0.48) | IDO1NOTUMCYP3A4CYP2D6LMNA | |
| SCHEMBL18288736 | 0.74 | CYP3A4 (0.52) | IDO1NOTUMCYP3A4CYP2D6LMNA | |
| SCHEMBL5224027 | 0.74 | CYP11B1 (0.53) | IDO1NOTUMCYP3A4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | claimed |
| CN-107245055-A | The preparation method of iprodione | 江苏蓝丰生物化工股份有限公司 | 2017-10-13 | — | — | CN | disclosed |