Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PCK1 | P35558 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL831663 | 0.93 | CYP2C8 (0.60) | CYP2C8FAAHRAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL831646 | 0.84 | CYP2C8 (0.74) | CYP2C8FAAH | |
| SCHEMBL832518 | 0.78 | CYP2C8 (0.79) | CYP2C8FAAH | |
| SCHEMBL832172 | 0.78 | CYP2C8 (0.76) | CYP2C8 | |
| SCHEMBL12665636 | 0.78 | CYP2C8 (0.78) | CYP2C8FAAH | |
| SCHEMBL831650 | 0.78 | CYP2C8 (0.65) | CYP2C8FAAHRAB9ASMN1; SMN2 | |
| SCHEMBL862278 | 0.77 | CYP2C8 (0.64) | CYP2C8FAAH | |
| SCHEMBL13905194 | 0.76 | CYP2C8 (0.61) | CYP2C8SMN1; SMN2 | |
| SCHEMBL8859155 | 0.75 | CYP2C8 (0.68) | CYP2C8 | |
| SCHEMBL832191 | 0.75 | CYP2C8 (0.51) | CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143305-B2 | 2,3-substituted indole derivatives for treating viral infections | SCHERING CORPORATION (US) | 2012-03-27 | — | — | US | disclosed |