Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 17/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334481 | 0.78 | DPP4 (0.71) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8335637 | 0.78 | DPP4 (0.49) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL5935823 | 0.78 | DPP4 (0.47) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL5487304 | 0.75 | DPP4 (0.67) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8335635 | 0.74 | DPP4 (0.67) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL4736463 | 0.74 | DPP4 (0.75) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL12862439 | 0.74 | DPP4 (0.75) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL25842321 | 0.74 | DPP4 (0.76) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL14687898 | 0.73 | DPP4 (0.68) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL1509250 | 0.73 | DPP4 (0.68) | DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058266-A1 | 3-AMINO-4-PHENYLBUTANOIC ACID DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO., INC. (US) | 2004-07-15 | — | — | WO | disclosed |