Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | SORD | Q00796 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21353591 | 0.83 | — | — | |
| SCHEMBL29857922 | 0.83 | PLD1 (0.73) | PLD1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15800694 | 0.83 | PLD1 (0.73) | PLD1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL159733 | 0.78 | PLD1 (0.61) | PLD1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL29904791 | 0.78 | PLD1 (0.61) | PLD1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL13711971 | 0.77 | KCNH2 (0.71) | ALDH1A1POLBKCNH2HTR1A | |
| SCHEMBL5548801 | 0.76 | HRH4 (0.44) | ALDH1A1KDM4E | |
| SCHEMBL29462629 | 0.75 | PLD1 (0.68) | PLD1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL230367 | 0.75 | PLD1 (0.68) | PLD1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL18228078 | 0.75 | PLD1 (0.68) | PLD1ALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | claimed |