SCHEMBL8334441

SCHEMBL8334441

CC(C)(C)[Si](C)(C)OC1CC(CO)(CO)C1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPM1D O15297 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2376304 0.81 PPM1D (0.40) PPM1D
SCHEMBL20561273 0.80 PPM1D (0.34) PPM1D
SCHEMBL20087739 0.78 PPM1D (0.40) PPM1D
SCHEMBL3186681 0.77 PPM1D (0.44) PPM1D
SCHEMBL2282440 0.77 PPM1D (0.41) PPM1D
SCHEMBL26323710 0.77 PPM1D (0.44) PPM1D
SCHEMBL29695186 0.77 PPM1D (0.39) PPM1D
SCHEMBL23704804 0.76 PPM1D (0.37) PPM1D
SCHEMBL25497955 0.75 PPM1D (0.36) PPM1D
SCHEMBL22362844 0.74 PPM1D (0.37) PPM1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999007706-A1 QUINOLONE CARBOXYLIC ACID DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1999-02-18 WO disclosed