Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | MAP3K5 | Q99683 | 8/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | MAX | P61244 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897019 | 0.88 | MEN1 (0.64) | MEN1KMT2APOLBTNFRSF1ASYK | |
| SCHEMBL3897021 | 0.88 | MEN1 (0.64) | MEN1KMT2APOLBTNFRSF1ASYK | |
| SCHEMBL6107999 | 0.82 | MAP3K5 (0.73) | MEN1KMT2APOLBTNFRSF1ASYK | |
| SCHEMBL6108001 | 0.82 | MAP3K5 (0.73) | MEN1KMT2APOLBTNFRSF1ASYK | |
| SCHEMBL3126558 | 0.79 | POLB (0.80) | MEN1KMT2APOLBMAP3K5ENPP2 | |
| SCHEMBL3126564 | 0.79 | POLB (0.80) | MEN1KMT2APOLBMAP3K5ENPP2 | |
| SCHEMBL3126561 | 0.79 | POLB (0.80) | MEN1KMT2APOLBMAP3K5ENPP2 | |
| SCHEMBL3135207 | 0.78 | TNFRSF1A (0.68) | MEN1KMT2ATNFRSF1ASYKMAP3K5 | |
| SCHEMBL3135211 | 0.78 | TNFRSF1A (0.68) | MEN1KMT2ATNFRSF1ASYKMAP3K5 | |
| SCHEMBL3135217 | 0.78 | TNFRSF1A (0.68) | MEN1KMT2ATNFRSF1ASYKMAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043955-A1 | RHODANINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RIGEL PHARMACEUTICALS, INC. (US) | 2004-05-27 | — | — | WO | disclosed |