Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.59 |
| ▸ | MEN1 | O00255 | 9/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6715520 | 0.92 | MEN1 (0.69) | KMT2AMEN1LMNAPOLBMAPK1 | |
| SCHEMBL6719557 | 0.89 | KMT2A (0.67) | KMT2AMEN1LMNAPOLBMAPK1 | |
| SCHEMBL6719654 | 0.88 | MEN1 (0.66) | KMT2AMEN1LMNAPOLBMAPK1 | |
| SCHEMBL6719353 | 0.88 | MEN1 (0.66) | KMT2AMEN1LMNAPOLBMAPK1 | |
| SCHEMBL6726961 | 0.88 | MEN1 (0.66) | KMT2AMEN1LMNAPOLBMAPK1 | |
| SCHEMBL6719596 | 0.87 | MEN1 (0.64) | KMT2AMEN1LMNAPOLBMAPK1 | |
| SCHEMBL6719997 | 0.87 | MEN1 (0.64) | KMT2AMEN1LMNAPOLBMAPK1 | |
| SCHEMBL6718096 | 0.87 | MEN1 (0.64) | KMT2AMEN1LMNAPOLBMAPK1 | |
| SCHEMBL6726796 | 0.86 | KMT2A (0.62) | KMT2AMEN1LMNAPOLBMAPK1 | |
| SCHEMBL6719705 | 0.84 | MEN1 (0.61) | KMT2AMEN1LMNAPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |