Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 13/20 | 1.00 |
| ▸ | PDE3A | Q14432 | 13/20 | 1.00 |
| ▸ | PDE5A | O76074 | 8/20 | 0.54 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714340 | 0.80 | PDE3B (0.69) | PDE3BPDE3APDE5APDE4APDE4B | |
| SCHEMBL714341 | 0.80 | PDE3B (0.69) | PDE3BPDE3APDE5APDE4APDE4B | |
| SCHEMBL10201625 | 0.80 | PDE5A (0.78) | PDE3BPDE3APDE5APDE4APDE4B | |
| SCHEMBL16503588 | 0.64 | PDE5A (0.52) | PDE3BPDE3APDE5APDE4APDE4B | |
| SCHEMBL149367 | 0.63 | PDE5A (1.00) | PDE3BPDE3APDE5APDE4APDE4B | |
| SCHEMBL194125 | 0.62 | PDE5A (0.59) | PDE3BPDE3APDE5APDE4APDE4B | |
| SCHEMBL230741 | 0.58 | PDE5A (0.61) | PDE3BPDE3APDE5APDE4APDE4B | |
| Hydrochloric Acid SCHEMBL7441962 | 0.57 | PDE5A (0.60) | PDE3BPDE3APDE5APDE4APDE4B | |
| SCHEMBL233561 | 0.57 | PDE5A (0.56) | PDE3BPDE3APDE5APDE4APDE4B | |
| Hydrochloric Acid SCHEMBL7430875 | 0.57 | PDE5A (0.60) | PDE3BPDE3APDE5APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037262-A2 | IMMEDIATE RELEASE TOPICAL PHARMACEUTICAL FORMULATION FOR ENHANCEMENT OF FEMALE SEXUAL DESIRE AND RESPONSIVENESS | VIVUS, INC. (US) | 2004-05-06 | — | — | WO | disclosed |
| WO-2003000343-A2 | ADMINISTRATION OF PHOSPHODIESTERASE INHIBITORS FOR THE TREATMENT OF PREMATURE EJACULATION | VIVUS, INC. (US) | 2003-01-03 | — | — | WO | disclosed |