SCHEMBL833518

SCHEMBL833518

O=[C]C(Cl)(Cl)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL835305 0.69
SCHEMBL4625363 0.67
SCHEMBL832084 0.65
SCHEMBL3501072 0.64
SCHEMBL1382 0.62
SCHEMBL514035 0.62
SCHEMBL8406569 0.62
SCHEMBL11875464 0.59
SCHEMBL135417 0.59
SCHEMBL7128824 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3274358-B1 VACCINE AGAINST CARBAPENEM-RESISTANTKLEBSIELLA PNEUMONIAE MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS EV (DE) 2020-09-16 EP claimed
US-20050250795-A1 Synthesis of acyclic nucleoside derivatives MEDIVIR AB (SE) 2005-11-10 US claimed
US-6184376-B1 POTENT ANTIVIRALS, ESPECIALLY AGAINST HERPES INFECTIONS, SUCH AS THOSE CAUSED BY VARICELLA ZOSTER VIRUS, HERPES SIMPLEX, EPSTEIN-BARR VIRUS, HERPES TYPE 6 (HHV-6) AND TYPE 8 (HHV-8). SHINGLES IN THE ELDERLY OR CHICKEN POX IN THE YOUNG MEDIVER AB (SE) 2001-02-06 US claimed
EP-0296749-A1 (Substituted aralkyl) heterocyclic compounds ZENECA LIMITED (GB) 1988-12-28 EP claimed
US-4458089-A ANTITUMOR AGENTS, MICROBIOCIDES THE UPJOHN COMPANY (US) 1984-07-03 US claimed
US-4107432-A ANTIBIOTICS MERCK & CO., INC. (US) 1978-08-15 US claimed
US-4058661-A 7-Diacyl cephalosporins MERCK & CO., INC. (US) 1977-11-15 US claimed
EP-3957627-B1 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SHIONOGI & CO (JP) 2024-06-19 EP disclosed
CN-111448205-B Vaccine against klebsiella pneumoniae 爱杜西亚药品有限公司 2024-05-14 CN disclosed
US-11685740-B2 Bicyclic nitrogen-containing heterocyclic derivatives and pharmaceutical composition comprising the same SHIONOGI & CO., LTD. (JP) 2023-06-27 US disclosed
US-20230119227-A1 OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT INTEGRATED DNA TECHNOLOGIES, INC. 2023-04-20 US disclosed
US-11541023-B2 Compounds and compositions for the treatment of neurodegenerative and inflammatory diseases SARBONNE UNIVERSITE (FR) 2023-01-03 US disclosed
CN-115135663-A Oligonucleotide synthesis on solid support 合成DNA技术公司 2022-09-30 CN disclosed
US-4366316-A FROM OXAZOLINOAZETIDINONE AND ACID SHIONOGI & CO., LTD. (JP) 1982-12-28 US disclosed
US-4355160-A Thiazolylacetamido cephalosporin type compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1982-10-19 US disclosed
EP-0045198-A2 1,1-Disubstituted carba-2-penems and their production Takeda Chemical Industries, Ltd. (JP) 1982-02-03 EP disclosed
US-4298606-A Thiazolylacetamido compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-11-03 US disclosed
US-4205180-A CHEMICAL INTERMEDIATES FOR NOVEL CEPHALOSPORIN COMPOUNDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1980-05-27 US disclosed
US-4203899-A Thiazolylacetamido compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1980-05-20 US disclosed
US-4098888-A THIAZOLYLACETAMIDO CEPHALOSPORIN TYPE COMPOUNDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1978-07-04 US disclosed