Clorophene

Clorophene

SCHEMBL8335308

Cc1c(Cl)ccc(O)c1Cc1ccccc1.Oc1ccc(Cl)cc1Cc1ccccc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.70
KMT2A Q03164 4/20 0.70
HIF1A Q16665 3/20 0.70
CYP3A4 P08684 3/20 0.70
HPGD P15428 2/20 0.70
ALOX15 P16050 2/20 0.70
HSD17B10 Q99714 1/20 0.70
MAPT P10636 4/20 0.50
LMNA P02545 2/20 0.50
HTT P42858 2/20 0.50
SLC22A1 O15245 1/20 0.50
USP2 O75604 1/20 0.50
HSP90AA1 P07900 1/20 0.50
HSPD1 P10809 1/20 0.50
HSPA5 P11021 1/20 0.50
IDO1 P14902 1/20 0.50
ALOX12 P18054 1/20 0.50
CASP1 P29466 1/20 0.50
BLM P54132 1/20 0.50
HSPE1 P61604 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL560333 0.87 MEN1 (0.46) MEN1KMT2AHIF1ACYP3A4HPGD
Parachlorophenol SCHEMBL6914323 0.86 MEN1 (0.47) MEN1KMT2AHIF1ACYP3A4HPGD
Clorophene SCHEMBL29377427 0.84 HIF1A (1.00) MEN1KMT2AHIF1ACYP3A4HPGD
Clorophene SCHEMBL78119 0.84 HIF1A (1.00) MEN1KMT2AHIF1ACYP3A4HPGD
Clorophene SCHEMBL30741300 0.82 HIF1A (0.96) MEN1KMT2AHIF1ACYP3A4HPGD
Clorophene SCHEMBL2811942 0.82 HIF1A (0.96) MEN1KMT2AHIF1ACYP3A4HPGD
Clorophene SCHEMBL29827182 0.82 HIF1A (0.96) MEN1KMT2AHIF1ACYP3A4HPGD
Clorophene SCHEMBL2806718 0.82 HIF1A (0.96) MEN1KMT2AHIF1ACYP3A4HPGD
Dichlorophen SCHEMBL7043835 0.82 HIF1A (0.96) MEN1KMT2AHIF1ACYP3A4HPGD
Clorophene SCHEMBL5160758 0.82 HIF1A (0.96) MEN1KMT2AHIF1ACYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805672-A4 METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH HOMOLA ANDREW M (US) 1999-06-30 EP disclosed
EP-0805672-A1 METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH HOMOLA, Andrew M. (US) 1997-11-12 EP disclosed
WO-1996022078-A1 METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH HOMOLA ANDREW M (US) 1996-07-25 WO disclosed