Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IARS1 | P41252 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336088 | 0.97 | EPHX2 (0.36) | L3MBTL1GAAKMT2AEPHX2IARS1 | |
| SCHEMBL8339542 | 0.96 | EPHX2 (0.38) | L3MBTL1GAAEPHX2 | |
| SCHEMBL8340047 | 0.96 | EPHX2 (0.38) | L3MBTL1GAAEPHX2 | |
| SCHEMBL8335636 | 0.96 | EPHX2 (0.38) | L3MBTL1GAAEPHX2 | |
| SCHEMBL8334742 | 0.94 | GAA (0.37) | L3MBTL1GAAKMT2ALMNAMAPT | |
| SCHEMBL8336550 | 0.91 | GAA (0.38) | L3MBTL1GAACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8340166 | 0.89 | GAA (0.39) | L3MBTL1GAAKMT2ALMNAMAPT | |
| SCHEMBL8336366 | 0.88 | GAA (0.38) | L3MBTL1GAAKMT2AEPHX2 | |
| SCHEMBL8338458 | 0.87 | GAA (0.37) | L3MBTL1GAAKMT2AEPHX2 | |
| SCHEMBL8339075 | 0.87 | GAA (0.37) | L3MBTL1GAAKMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977177-A | Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |