Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340639 | 0.95 | CNR2 (0.41) | CNR2CNR1MAPTESR1ESR2 | |
| SCHEMBL8336077 | 0.93 | MCL1 (0.40) | CNR2MAPTCYP1A2CYP2C19MCL1 | |
| SCHEMBL8336809 | 0.88 | CNR2 (0.47) | CNR2CNR1MAPTMEN1KMT2A | |
| SCHEMBL8339168 | 0.88 | MCL1 (0.38) | CNR2MAPTESR1ESR2CYP1A2 | |
| SCHEMBL8336383 | 0.86 | CNR2 (0.40) | CNR2CNR1MAPTESR1ESR2 | |
| SCHEMBL8334344 | 0.86 | MAPT (0.38) | CNR2CNR1MAPTMEN1KMT2A | |
| SCHEMBL8336646 | 0.86 | CNR2 (0.35) | CNR2MAPTCYP1A2CYP2C19MCL1 | |
| SCHEMBL8335888 | 0.86 | C5AR1 (0.38) | CNR2MCL1BCL2BCL2L1BAD | |
| SCHEMBL8336090 | 0.86 | MAPT (0.39) | CNR2CNR1MAPTESR1ESR2 | |
| SCHEMBL8339826 | 0.84 | KDM4E (0.42) | CNR2CNR1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948796-A | OSTEOPOROSIS, CANCER, CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1999-09-07 | — | — | US | disclosed |