Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.37 |
| ▸ | F10 | P00742 | 6/20 | 0.35 |
| ▸ | F7 | P08709 | 5/20 | 0.35 |
| ▸ | F3 | P13726 | 5/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340137 | 0.89 | F10 (0.38) | PTGER1MRGPRX4F10F7F3 | |
| SCHEMBL6578738 | 0.80 | MRGPRX4 (0.43) | PTGER1MRGPRX4F10F7F3 | |
| SCHEMBL8336242 | 0.78 | F7 (0.41) | PTGER1MRGPRX4F10F7F3 | |
| SCHEMBL6580856 | 0.69 | MEN1 (0.44) | MRGPRX4F10F7F3 | |
| SCHEMBL6579083 | 0.67 | F10 (0.44) | PTGER1MRGPRX4F10PLAUPLG | |
| SCHEMBL6581757 | 0.67 | MRGPRX4 (0.46) | PTGER1MRGPRX4 | |
| SCHEMBL6579202 | 0.66 | F10 (0.43) | PTGER1F10SLC6A9PLAUPLG | |
| SCHEMBL6581766 | 0.66 | MRGPRX4 (0.52) | PTGER1MRGPRX4F10 | |
| SCHEMBL6578675 | 0.66 | F2 (0.47) | PTGER1MRGPRX4F10PLAU | |
| SCHEMBL6774708 | 0.66 | TTR (0.42) | F10F7F3PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889005-A | Benzamidine derivatives and their use for treating thrombotic diseases | BERLEX LABORATORIES, INC. (US) | 1999-03-30 | — | — | US | disclosed |
| US-5883100-A | Benzamidine derivatives and their use as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1999-03-16 | — | — | US | disclosed |
| US-5877181-A | Benzamidine derivatives and their use as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1999-03-02 | — | — | US | disclosed |
| US-5691364-A | Benzamidine derivatives and their use as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1997-11-25 | — | — | US | disclosed |