Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334700 | 0.92 | ECE1 (0.85) | ECE1 | |
| SCHEMBL6019297 | 0.85 | ECE1 (0.74) | ECE1 | |
| SCHEMBL6020357 | 0.84 | ECE1 (0.73) | ECE1 | |
| SCHEMBL8360497 | 0.84 | ECE1 (0.98) | ECE1 | |
| SCHEMBL8330085 | 0.83 | ECE1 (0.85) | ECE1 | |
| SCHEMBL8362936 | 0.82 | ECE1 (0.79) | ECE1 | |
| SCHEMBL8337542 | 0.80 | ECE1 (0.75) | ECE1 | |
| SCHEMBL6020407 | 0.79 | ECE1 (0.73) | ECE1 | |
| SCHEMBL6019372 | 0.79 | ECE1 (0.76) | ECE1 | |
| SCHEMBL6020370 | 0.79 | ECE1 (1.00) | ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056768-A2 | USE OF SUBSTITUTED 2,5-DIAMIDOINDOLES FOR THE TREATMENT OF UROLOGICAL DISEASES | BAYER HEALTHCARE AG (DE) | 2004-07-08 | — | — | WO | disclosed |
| WO-2003028719-A1 | SUBSTITUTED 2,5-DIAMIDOINDOLES AS ECE INHIBITORS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2003-04-10 | — | — | WO | disclosed |