Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GPR17 | Q13304 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499308 | 0.81 | GRIN1 (0.59) | GRIN1GPR17MEN1LMNACYP1A2 | |
| SCHEMBL499309 | 0.81 | GRIN1 (0.59) | GRIN1GPR17MEN1LMNACYP1A2 | |
| SCHEMBL4422661 | 0.80 | GRIN1 (0.58) | GRIN1GPR17MEN1LMNACYP1A2 | |
| SCHEMBL4422653 | 0.80 | GRIN1 (0.58) | GRIN1GPR17MEN1LMNACYP1A2 | |
| SCHEMBL8190768 | 0.76 | GRIN1 (0.55) | GRIN1GPR17MEN1LMNACYP1A2 | |
| SCHEMBL8190756 | 0.76 | GRIN1 (0.55) | GRIN1GPR17MEN1LMNACYP1A2 | |
| SCHEMBL8181067 | 0.75 | GRIN1 (0.54) | GRIN1GPR17MEN1LMNACYP1A2 | |
| SCHEMBL8181079 | 0.75 | GRIN1 (0.54) | GRIN1GPR17MEN1LMNACYP1A2 | |
| SCHEMBL1720270 | 0.73 | GRIN1 (0.52) | GRIN1MEN1LMNACYP1A2MAPK1 | |
| SCHEMBL30521938 | 0.73 | GRIN1 (0.52) | GRIN1MEN1LMNACYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039371-A2 | COMPOSITIONS OF CYCLOOXYGENASE-2 SELECTIVE INHIBITORS AND NMDA RECEPTOR ANTAGONISTS FOR THE TREATMENT OR PREVENTION OF NEUROPATHIC PAIN | PHARMACIA CORPORATION (US) | 2004-05-13 | — | — | WO | disclosed |