Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8331805 | 0.82 | GAA (0.51) | GAAABL1HTTKDM4ENQO2 | |
| SCHEMBL13315462 | 0.80 | GAA (0.46) | GAAABL1HTTKDM4EMAPT | |
| SCHEMBL522450 | 0.79 | GAA (0.49) | GAAABL1HTTKDM4ENQO2 | |
| SCHEMBL8159962 | 0.79 | GAA (0.49) | GAAABL1HTTKDM4EMAPT | |
| SCHEMBL31147102 | 0.79 | GAA (0.51) | GAAABL1HTTKDM4EMAPT | |
| SCHEMBL28406215 | 0.78 | ABL1 (0.46) | GAAABL1HTTMAPTNPSR1 | |
| SCHEMBL7409881 | 0.78 | ABL1 (0.46) | GAAABL1HTTKDM4EMAPT | |
| SCHEMBL70011 | 0.78 | GAA (0.58) | GAAABL1HTTKDM4EMAPT | |
| SCHEMBL1953848 | 0.78 | GAA (0.58) | GAAABL1HTTKDM4EMAPT | |
| SCHEMBL27214471 | 0.77 | SOS1 (0.46) | GAAABL1HTTMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070466-C | Method for preparing aromatic compounds | ROHM & HAAS (US) | 2001-09-05 | — | — | CN | disclosed |
| US-5886210-A | Method for preparing aromatic compounds | ROHM AND HAAS COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| CN-1186795-A | Method for preparing aromatic compounds | ROHM & HAAS (US) | 1998-07-08 | — | — | CN | disclosed |
| EP-0825173-A1 | Method for preparing aromatic compounds | ROHM AND HAAS COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |