Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335452 | 0.90 | GSK3B (0.58) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL8338070 | 0.90 | GSK3B (0.59) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL8337413 | 0.90 | GSK3B (0.60) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL2857709 | 0.90 | GSK3B (0.62) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL15435943 | 0.89 | GSK3B (0.59) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8334435 | 0.89 | GSK3B (0.50) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8337421 | 0.89 | GSK3B (0.54) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL8337420 | 0.88 | GSK3B (0.62) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8335448 | 0.87 | GSK3B (0.60) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8337192 | 0.86 | GSK3B (0.58) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572681-B1 | 3-SUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI TANABE PHARMA CORP (JP) | 2014-01-22 | — | — | EP | disclosed |
| WO-2004055007-A1 | 3-SUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2004-07-01 | — | — | WO | disclosed |