Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL905275 | 0.84 | HSD17B10 (0.42) | NR1H2NR1H3EPHX2USP2SMN1; SMN2 | |
| SCHEMBL16369976 | 0.84 | HSD17B10 (0.42) | NR1H2NR1H3EPHX2USP2SMN1; SMN2 | |
| SCHEMBL16409169 | 0.84 | USP2 (0.37) | NR1H2NR1H3EPHX2USP2SMN1; SMN2 | |
| SCHEMBL16409170 | 0.84 | USP2 (0.37) | NR1H2NR1H3EPHX2USP2SMN1; SMN2 | |
| SCHEMBL905280 | 0.84 | HSD17B10 (0.42) | NR1H2NR1H3EPHX2USP2SMN1; SMN2 | |
| SCHEMBL30181505 | 0.84 | MEN1 (0.39) | ALDH1A1HSD17B10 | |
| SCHEMBL16914271 | 0.84 | NR1H2 (0.35) | NR1H2NR1H3EPHX2PTPN1USP2 | |
| SCHEMBL16391183 | 0.81 | USP2 (0.34) | NR1H2EPHX2USP2SMN1; SMN2HSD17B10 | |
| SCHEMBL16391172 | 0.81 | USP2 (0.34) | NR1H2EPHX2USP2SMN1; SMN2HSD17B10 | |
| SCHEMBL17191520 | 0.81 | USP2 (0.34) | NR1H2EPHX2USP2SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026866-A1 | N-AROYL CYCLIC AMINES AS OREXIN RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2004-04-01 | — | — | WO | disclosed |