Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15777897 | 0.88 | ABL1 (0.49) | NPC1RAB9ASMN1; SMN2MAPTCASP3 | |
| SCHEMBL20476379 | 0.88 | PPARA (0.57) | NPC1RAB9ASMN1; SMN2MAPTCASP3 | |
| SCHEMBL20077738 | 0.86 | SMN1; SMN2 (0.57) | NPC1RAB9ASMN1; SMN2MAPTCASP3 | |
| SCHEMBL26270868 | 0.85 | MAPT (0.51) | NPC1RAB9ASMN1; SMN2MAPTCASP3 | |
| SCHEMBL23582687 | 0.84 | FFAR4 (0.54) | NPC1RAB9ASMN1; SMN2MAPTCASP3 | |
| SCHEMBL29847225 | 0.84 | FFAR4 (0.54) | NPC1RAB9ASMN1; SMN2MAPTCASP3 | |
| SCHEMBL1515906 | 0.83 | CA12 (0.51) | NPC1RAB9ASMN1; SMN2MAPTCASP3 | |
| SCHEMBL7015377 | 0.83 | ABL1 (0.47) | NPC1RAB9ASMN1; SMN2MAPTCASP3 | |
| SCHEMBL23582707 | 0.83 | ABL1 (0.45) | NPC1RAB9ASMN1; SMN2MAPTCASP3 | |
| SCHEMBL9472713 | 0.83 | PDK2 (0.44) | NPC1RAB9ASMN1; SMN2MAPTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101868444-A | Acetylenic compound, salt thereof, condensate thereof, and composition thereof | FUJIFILM CORP | 2010-10-20 | — | — | CN | disclosed |
| US-5856574-A | ANTIISCHEMIC AGENTS; ANTIARRTHYMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-01-05 | — | — | US | disclosed |