SCHEMBL8339302

SCHEMBL8339302

Cc1cc(OC/C=C(/F)Br)cc(Cl)c1OCCCOc1ccc(C(F)(F)F)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 9/20 0.40
PPARA Q07869 6/20 0.37
PPARG P37231 4/20 0.37
MAOB P27338 1/20 0.36
AOC3 Q16853 1/20 0.36
RHOC P08134 1/20 0.35
RHOA P61586 1/20 0.35
SCN8A Q9UQD0 1/20 0.35
CYP3A4 P08684 1/20 0.34
KCNH2 Q12809 1/20 0.34
CACNA1C Q13936 1/20 0.34
SCN5A Q14524 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34
MCL1 Q07820 2/20 0.34
MAPT P10636 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8339303 1.00 PPARD (0.40) PPARDPPARAPPARGMAOBAOC3
SCHEMBL8344192 0.98 PPARD (0.40) PPARDPPARAPPARGMAOBAOC3
SCHEMBL8344195 0.98 PPARD (0.40) PPARDPPARAPPARGMAOBAOC3
SCHEMBL8410687 0.92 MAOB (0.40) PPARDPPARAMAOBAOC3RHOC
SCHEMBL8410686 0.92 MAOB (0.40) PPARDPPARAMAOBAOC3RHOC
SCHEMBL8341308 0.91 PPARD (0.38) PPARDPPARAPPARGMAOBAOC3
SCHEMBL8341315 0.91 PPARD (0.38) PPARDPPARAPPARGMAOBAOC3
SCHEMBL8339294 0.90 MAOB (0.40) PPARDPPARAMAOBAOC3RHOC
SCHEMBL8339298 0.90 MAOB (0.40) PPARDPPARAMAOBAOC3RHOC
SCHEMBL8408877 0.89 PPARD (0.40) PPARDPPARAPPARGMAOBAOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0787710-B1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 1999-07-28 EP disclosed
US-5869506-A APPLYING TO ACARIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-09 US disclosed
EP-0787710-A1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-06 EP disclosed