Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KDM6A | O15550 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KDM5C | P41229 | 1/20 | 0.51 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.51 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | COMT | P21964 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 10/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2511741 | 0.84 | KDM4E (0.57) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL8102115 | 0.83 | KDM4E (0.55) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL21523588 | 0.83 | KDM4E (0.55) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL3290957 | 0.81 | APP (0.57) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL113697 | 0.80 | KDM4E (0.47) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL113619 | 0.80 | KDM4E (0.47) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL113644 | 0.80 | KDM4E (0.47) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL17285292 | 0.78 | KDM4E (0.57) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL113661 | 0.78 | APP (0.51) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL13003558 | 0.77 | KDM4E (0.60) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041151-A2 | NEUROPROTECTIVE IRON CHELATORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2004-05-21 | — | — | WO | disclosed |