⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL19837703 | 0.97 | — | — | |
| SCHEMBL7771187 | 0.88 | TSHR (0.33) | — | |
| SCHEMBL3902911 | 0.87 | — | — | |
| SCHEMBL3890027 | 0.87 | — | — | |
| SCHEMBL28716435 | 0.84 | CA1 (0.37) | — | |
| SCHEMBL1014426 | 0.84 | CA1 (0.37) | — | |
| SCHEMBL29161823 | 0.84 | CA1 (0.37) | — | |
| SCHEMBL29183706 | 0.84 | — | — | |
| SCHEMBL29006344 | 0.84 | CA1 (0.37) | — | |
| SCHEMBL30838783 | 0.84 | CA1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 341 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775259-B | Amatinib intermediate Synthesis method of intermediate | 烟台舜康生物科技有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119775259-A | Amatinib intermediate Synthesis method of intermediate | 烟台舜康生物科技有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-118930568-A | Rapid synthesis method of polysubstituted pyrimidine bromine and pyrimidine boric acid compound | 南通益昊药业有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-118745181-A | Wnt pathway inhibitor compounds | 杭州阿诺生物医药科技有限公司 | 2024-10-08 | — | — | CN | claimed |
| CN-118666879-A | Method for synthesizing chiral aryl/alkyl substituted cyclopropyl borate | 华东师范大学 | 2024-09-20 | — | — | CN | claimed |
| CN-118344277-A | Pyrrole derivative and preparation method and application thereof | 山东大学 | 2024-07-16 | — | — | CN | claimed |
| CN-118307570-A | Cyclopropyl borate compound and preparation method thereof | 南方科技大学 | 2024-07-09 | — | — | CN | claimed |
| CN-117820075-A | Synthesis method of 4-bromo-2-cyclopropyl-benzotrifluoride | 吉尔多肽生物制药(大连市)有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-113735889-B | Process method for synthesizing cyclopropylboric acid | 大连双硼医药化工有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-115677545-B | anti-HBV sulfonamide derivative and preparation method and application thereof | 潍坊医学院 | 2024-03-15 | — | — | CN | claimed |
| CN-114933801-B | Rubber composition based on modified retired silicon rubber insulator and preparation method thereof | 广东电网有限责任公司 | 2023-12-22 | — | — | CN | claimed |
| CN-115368243-B | Gradient oxygen doped MoS 2 Application in catalyzing C-N coupling reaction | 江苏科技大学 | 2023-11-21 | — | — | CN | claimed |
| CN-114874232-B | Preparation method and application of thienopyrimidinone compound containing ethyl naphthalene structure | 山东大学 | 2023-11-14 | — | — | CN | claimed |
| CN-116874406-A | Indolyl sulfonamide compound and preparation method and application thereof | 山东大学 | 2023-10-13 | — | — | CN | claimed |
| CN-114907344-B | Beta-carboline-1-propionic acid and indole derivatives, and preparation method and application thereof | 山东大学 | 2023-06-30 | — | — | CN | claimed |
| WO-2023040733-A1 | BAICALEIN DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2023-03-23 | — | — | WO | claimed |
| CN-115819391-A | Baicalein derivative, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-03-21 | — | — | CN | claimed |
| CN-112457289-A | Cyclopropyl thiophene methylamine compound or pharmaceutically acceptable salt thereof and application thereof | 横琴鲸准智慧医疗科技有限公司 | 2021-03-09 | — | — | CN | claimed |
| CN-108299486-B | Method for preparing cyclopropyl borate compound based on iron catalysis | 大连理工大学 | 2020-06-02 | — | — | CN | claimed |
| CN-111018752-A | Para-cyclopropanyl substituted benzene sulfonyl aniline and preparation method thereof | 郑州轻工业大学 | 2020-04-17 | — | — | CN | claimed |