Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.78 |
| ▸ | PPARG | P37231 | 14/20 | 0.60 |
| ▸ | PPARA | Q07869 | 14/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14514345 | 0.89 | KDR (0.78) | KDRPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL3526019 | 0.88 | KDR (0.73) | KDRPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL4034790 | 0.87 | KDR (1.00) | KDRPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL4031039 | 0.87 | KDR (0.74) | KDRPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5802990 | 0.86 | KDR (0.72) | KDRPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL4033640 | 0.85 | KDR (0.79) | KDRPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL8983760 | 0.84 | KDR (0.78) | KDRPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL4030470 | 0.84 | KDR (0.70) | KDRPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL6160505 | 0.84 | KDR (0.77) | KDRPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL14382593 | 0.84 | KDR (0.77) | KDRPPARGPPARACYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965589-A | AN ACTIVE MATERIAL HAVING HYPOGLYCEMIC ACTIVITY AND BLOOD LIPID LOWERING ACTIVITY, FOR USE AS AN ANTIDIABETIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0783496-A1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996005186-A1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-22 | — | — | WO | disclosed |