SCHEMBL8340302

SCHEMBL8340302

CN1CC[C@@H](Oc2cc(NS(=O)(=O)c3ccc(Br)cc3F)ccc2Cl)C1

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 13/20 0.69
NMT1 P30419 1/20 0.43
FPR2 P25090 1/20 0.41
PROKR1 Q8TCW9 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
SCN8A Q9UQD0 2/20 0.40
SCN1A P35498 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5835494 0.90 UTS2R (0.70) UTS2RMEN1ALDH1A1LMNAMAPT
SCHEMBL5835495 0.90 UTS2R (0.70) UTS2RMEN1ALDH1A1LMNAMAPT
SCHEMBL5835659 0.89 UTS2R (0.72) UTS2RSCN8ASCN1A
SCHEMBL5835297 0.89 UTS2R (0.72) UTS2RSCN8ASCN1A
SCHEMBL5835652 0.89 UTS2R (0.72) UTS2RSCN8ASCN1A
SCHEMBL5835293 0.89 UTS2R (0.72) UTS2RSCN8ASCN1A
SCHEMBL5835611 0.87 UTS2R (0.67) UTS2RSCN8ASCN1A
SCHEMBL5835605 0.87 UTS2R (0.67) UTS2RSCN8ASCN1A
SCHEMBL5834932 0.87 UTS2R (0.67) UTS2RSCN8ASCN1A
SCHEMBL5834931 0.87 UTS2R (0.67) UTS2RSCN8ASCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043366-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed