Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340279 | 0.76 | — | — | |
| SCHEMBL8340012 | 0.71 | NPSR1 (0.32) | NPSR1ALDH1A1 | |
| SCHEMBL7709177 | 0.69 | GRM1 (0.44) | GRM5GRM1CYP2D6LMNAEGFR | |
| SCHEMBL8337575 | 0.66 | GRM1 (0.49) | GRM5GRM1 | |
| SCHEMBL8340268 | 0.66 | — | — | |
| SCHEMBL8337390 | 0.65 | — | — | |
| SCHEMBL4664795 | 0.64 | GRM1 (0.49) | GRM5GRM1CYP2D6LMNAEGFR | |
| SCHEMBL8340330 | 0.63 | — | — | |
| SCHEMBL28754501 | 0.63 | GRM1 (0.42) | GRM5GRM1CYP2D6LMNAEGFR | |
| SCHEMBL13319990 | 0.60 | CYP2D6 (0.46) | GRM5GRM1CYP2D6LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024709-A2 | XANTHENYL CUBANE ANALOGS WITH ACTIVITY AT THE METABOTROPIC GLUTAMATE RECEPTORS | PRESCIENT NEUROPHARMA INC. (CA) | 2004-03-25 | — | — | WO | disclosed |