Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 4/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.41 |
| ▸ | GRIK4 | Q16099 | 4/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340390 | 0.96 | GRIA1 (0.43) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8346061 | 0.86 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7354092 | 0.85 | GRIN1 (0.42) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8342344 | 0.84 | GRIK1 (0.42) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8342152 | 0.83 | GRIK1 (0.36) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8342457 | 0.83 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8342972 | 0.83 | GRIK1 (0.42) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8343088 | 0.83 | GRIK1 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8342975 | 0.82 | GRIK1 (0.47) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8342320 | 0.81 | GRIK1 (0.45) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955461-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5750525-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |