Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13915175 | 0.90 | GSK3B (0.53) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8342403 | 0.89 | GSK3B (0.53) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8338443 | 0.87 | GSK3B (0.49) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL88517 | 0.87 | GSK3B (0.55) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL1674428 | 0.85 | GSK3B (0.70) | GSK3BCYP2D6 | |
| SCHEMBL1673576 | 0.85 | GSK3B (0.70) | GSK3BCYP2D6 | |
| SCHEMBL497313 | 0.85 | GSK3B (0.70) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL497069 | 0.85 | GSK3B (0.70) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL13915177 | 0.85 | GSK3B (0.54) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL12806427 | 0.84 | GSK3B (0.55) | GSK3BCYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504411-B2 | 2,3,6-Trisubstituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |
| US-7504411-B2 | 2,3,6-Trisubstituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |
| WO-2004085408-A1 | 2, 3, 6-TRISUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2004-10-07 | — | — | WO | disclosed |