Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.68 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.61 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.61 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.61 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.61 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.61 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.61 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.61 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.61 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352040 | 0.96 | SLC22A6 (0.74) | SLC22A6SLC22A8GRIK1GRIA1GRIA2 | |
| SCHEMBL8346019 | 0.90 | SLC22A6 (0.66) | SLC22A6SLC22A8GRIK1GRIA1GRIA2 | |
| SCHEMBL8346068 | 0.87 | SLC22A6 (0.72) | SLC22A6SLC22A8GRIK1GRIA1GRIA2 | |
| SCHEMBL8124932 | 0.86 | SLC22A6 (0.61) | SLC22A6SLC22A8GRIK1GRIA1GRIA2 | |
| SCHEMBL8343057 | 0.85 | SLC22A6 (0.58) | SLC22A6SLC22A8GRIK1GRIA1GRIA2 | |
| SCHEMBL8192737 | 0.85 | SLC22A6 (0.92) | SLC22A6SLC22A8GRIK1GRIA1GRIA2 | |
| SCHEMBL8346030 | 0.83 | GRIK1 (0.59) | SLC22A6SLC22A8GRIK1GRIA1GRIA2 | |
| Zonampanel SCHEMBL678832 | 0.81 | SLC22A6 (1.00) | SLC22A6SLC22A8GRIK1GRIA1GRIA2 | |
| Hydrochloric Acid SCHEMBL8137201 | 0.81 | SLC22A6 (0.75) | SLC22A6SLC22A8GRIK1GRIA1GRIA2 | |
| Zonampanel SCHEMBL29379917 | 0.81 | SLC22A6 (1.00) | SLC22A6SLC22A8GRIK1GRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955461-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5750525-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |