Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.89 |
| ▸ | LMNA | P02545 | 2/20 | 0.89 |
| ▸ | BLM | P54132 | 2/20 | 0.89 |
| ▸ | MAPT | P10636 | 1/20 | 0.89 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.89 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cysteamine SCHEMBL16369 | 1.00 | — | — | |
| Cysteamine SCHEMBL1270405 | 1.00 | — | — | |
| Cysteamine SCHEMBL2357943 | 0.94 | — | — | |
| Cysteamine SCHEMBL21826833 | 0.94 | — | — | |
| Cysteamine SCHEMBL21981247 | 0.94 | — | — | |
| Cysteamine SCHEMBL25327317 | 0.94 | — | — | |
| Cysteamine SCHEMBL21826826 | 0.94 | — | — | |
| Cysteamine SCHEMBL25318894 | 0.94 | — | — | |
| Cysteamine SCHEMBL7624444 | 0.94 | — | — | |
| Cysteamine SCHEMBL19359033 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013062544-A1 | CYSTEAMINE IN THE TREATMENT OF FIBROTIC DISEASE | SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2013-05-02 | — | — | WO | disclosed |
| US-5907009-A | AMINO-CONTAINING LOW MOLECULAR WEIGHT DIENE POLYMER | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 1999-05-25 | — | — | US | disclosed |