Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.97 |
| ▸ | MAPT | P10636 | 1/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | HTR7 | P34969 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491551 | 0.86 | ABCB1 (0.78) | ABCB1MAPTSMN1; SMN2ATMCYP2D6 | |
| SCHEMBL491548 | 0.86 | ABCB1 (0.78) | ABCB1MAPTSMN1; SMN2ATMCYP2D6 | |
| SCHEMBL22639925 | 0.82 | TSHR (0.88) | ABCB1MAPTSMN1; SMN2ATMCYP2D6 | |
| SCHEMBL10200142 | 0.82 | TSHR (0.88) | ABCB1MAPTSMN1; SMN2ATMCYP2D6 | |
| SCHEMBL15445664 | 0.82 | TSHR (0.72) | ABCB1MAPTSMN1; SMN2ATMCYP2D6 | |
| SCHEMBL7953122 | 0.81 | TSHR (0.85) | ABCB1MAPTATMCYP2D6MEN1 | |
| SCHEMBL22640122 | 0.81 | TSHR (0.85) | ABCB1MAPTATMCYP2D6MEN1 | |
| SCHEMBL13033205 | 0.81 | MAPK1 (0.77) | ABCB1MAPTSMN1; SMN2POLBMAPK1 | |
| SCHEMBL21320448 | 0.80 | MAPK1 (0.67) | ABCB1MAPTSMN1; SMN2ATMCYP2D6 | |
| SCHEMBL16314604 | 0.80 | ATM (0.82) | ABCB1SMN1; SMN2ATMCYP2D6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007693-A1 | BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |