Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 13/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15577144 | 0.90 | GAA (0.51) | GAAMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10805263 | 0.84 | GAA (0.59) | GAAMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11197746 | 0.82 | GAA (0.67) | GAAMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5704002 | 0.82 | GAA (0.67) | GAAMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL112411 | 0.82 | GAA (0.67) | GAAMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29392652 | 0.82 | GAA (0.67) | GAAMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL116088 | 0.82 | GAA (0.70) | GAAMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4692876 | 0.82 | KAT2B (0.49) | GAAMAPTSMN1; SMN2RAB9APOLB | |
| Hydrochloric Acid SCHEMBL8114256 | 0.81 | GAA (0.65) | GAAMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11196756 | 0.80 | MAPT (0.68) | GAAMAPTSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955461-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5750525-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |