Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20976919 | 0.89 | SSTR1 (0.49) | GPR84HTR2AHTR1AADRB1ADRA2A | |
| SCHEMBL22680197 | 0.88 | HTR2A (0.47) | GPR84HTR2AHTR1AADRB1ADRA2A | |
| SCHEMBL21263604 | 0.88 | HTR2A (0.45) | GPR84HTR2AHTR1AADRB1ADRA2A | |
| SCHEMBL12582465 | 0.87 | SSTR3 (0.50) | GPR84HTR2AHTR1AADRB1ADRA2A | |
| SCHEMBL13579138 | 0.86 | SSTR3 (0.49) | SSTR1SSTR3MAPTKDM4EAPAF1 | |
| SCHEMBL14341130 | 0.85 | SSTR3 (0.48) | SSTR1SSTR3MAPTKDM4EAPAF1 | |
| SCHEMBL2342532 | 0.85 | SSTR3 (0.52) | SSTR1SSTR3MAPTKDM4EAPAF1 | |
| SCHEMBL1929182 | 0.85 | SSTR1 (0.46) | GPR84HTR2AHTR1AADRB1ADRA2A | |
| SCHEMBL1928410 | 0.85 | KCNT1 (0.48) | GPR84SSTR1SSTR3MEN1KMT2A | |
| SCHEMBL1927672 | 0.85 | KCNT1 (0.48) | GPR84SSTR1SSTR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200347110-A1 | Composition and Methods for Stimulating Gastrointestinal Motility | IPSEN PHARMA S.A.S. (FR) | 2020-11-05 | — | — | US | disclosed |
| EP-1937262-B1 | COMPOSITION FOR USE IN TREATING GASTROINTESTINAL DYSMOTILITY | IPSEN PHARMA (FR) | 2019-05-08 | — | — | EP | disclosed |
| US-20170037104-A1 | Composition and Methods for Stimulating Gastrointestinal Motility | IPSEN PHARMA S.A.S. (FR) | 2017-02-09 | — | — | US | disclosed |
| US-9499599-B2 | Composition and methods for stimulating gastrointestinal motility | IPSEN PHARMA S.A.S. (FR) | 2016-11-22 | — | — | US | disclosed |
| US-8981054-B2 | Compositions and methods for stimulating gastrointestinal motility | IPSEN PHARMA S.A.S. (FR) | 2015-03-17 | — | — | US | disclosed |
| US-20110166069-A1 | COMPOSITIONS AND METHODS FOR STIMULATING GASTROINTESTINAL MOTILITY | BIOMEASURE, INCORPORATED | 2011-07-07 | — | — | US | disclosed |
| EP-1542716-B1 | GROWTH HORMONE RELEASING PEPTIDES | IPSEN PHARMA (FR) | 2009-11-04 | — | — | EP | disclosed |
| WO-2004014415-A1 | GROWTH HORMONE RELEASING PEPTIDES | SOCIETE DE CONSEIL DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037104-A1 | Composition and Methods for Stimulating Gastrointestinal Motility | GIPR, VIP, GRPR | GPR84 209/4885HTR2A 690/4885HTR1A 423/4885 |
| US-20110166069-A1 | COMPOSITIONS AND METHODS FOR STIMULATING GASTROINTESTINAL MOTILITY | GIPR, VIP, GRPR | GPR84 251/4885HTR2A 850/4885HTR1A 508/4885 |
| US-20200347110-A1 | Composition and Methods for Stimulating Gastrointestinal Motility | GIPR, VIP, GRPR | GPR84 209/4885HTR2A 690/4885HTR1A 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.