⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21829069 | 0.75 | — | — | |
| SCHEMBL523748 | 0.72 | — | — | |
| SCHEMBL2879698 | 0.72 | — | — | |
| SCHEMBL1104730 | 0.72 | — | — | |
| Nitromethane SCHEMBL10992334 | 0.67 | — | — | |
| Iodide SCHEMBL114641 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL443366 | 0.67 | — | — | |
| SCHEMBL17090717 | 0.64 | — | — | |
| SCHEMBL9634898 | 0.64 | — | — | |
| SCHEMBL3175574 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12180145-B2 | Fused cyclooctyne compounds and their use in metal-free click reactions | SYNAFFIX B.V. (NL) | 2024-12-31 | — | — | US | claimed |
| US-20230102685-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX B.V. (NL) | 2023-03-30 | — | — | US | claimed |
| US-11358921-B2 | Fused cyclooctyne compounds and their use in metal-free click reactions | SYNAFFIX B.V. (NL) | 2022-06-14 | — | — | US | claimed |
| EP-2629608-B1 | PROTECTED ANTIMICROBIAL COMPOUNDS FOR HIGH TEMPERATURE APPLICATIONS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-07-13 | — | — | EP | claimed |
| US-9226499-B2 | Protected antimicrobial compounds for high temperature applications | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-01-05 | — | — | US | claimed |
| CN-103260404-B | Protected antimicrobial compounds for high temperature applications | DOW GLOBAL TECHNOLOGIES INC | 2015-04-01 | — | — | CN | claimed |
| US-20130267604-A1 | PROTECTED ANTIMICROBIAL COMPOUNDS FOR HIGH TEMPERATURE APPLICATIONS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-10-10 | — | — | US | claimed |
| EP-2629608-A1 | PROTECTED ANTIMICROBIAL COMPOUNDS FOR HIGH TEMPERATURE APPLICATIONS | ANGUS Chemical Company (US) | 2013-08-28 | — | — | EP | claimed |
| CN-103260404-A | Protected antimicrobial compounds for high temperature applications | ANGUS CHEMICAL COMPNAY | 2013-08-21 | — | — | CN | claimed |
| WO-2012082350-A1 | PROTECTED ANTIMICROBIAL COMPOUNDS FOR HIGH TEMPERATURE APPLICATIONS | ANGUS CHEMICAL COMPANY (US) | 2012-06-21 | — | — | WO | claimed |
| EP-0998467-A1 | PREPARATION AND USE OF 2-METHYL-5-PHENYLISOXAZOLIDINE | ALBEMARLE CORPORATION (US) | 2000-05-10 | — | — | EP | claimed |
| EP-0988278-A1 | PREPARATION AND USES OF N-METHYLNITRONE | ALBEMARLE CORPORATION (US) | 2000-03-29 | — | — | EP | claimed |
| US-5998627-A | Preparation and uses of hydrocarbylnitrones | ALBEMARLE CORPORATION (US) | 1999-12-07 | — | — | US | claimed |
| US-5917091-A | Preparation and use of 2-methyl-5-phenylisoxazolidine | ALBEMARLE CORPORATION (US) | 1999-06-29 | — | — | US | claimed |
| US-5892117-A | Preparation and uses of N-methylnitrone | ALBEMARLE CORPORATION (US) | 1999-04-06 | — | — | US | claimed |
| WO-1999005129-A1 | PREPARATION AND USE OF 2-METHYL-5-PHENYLISOXAZOLIDINE | ALBEMARLE CORPORATION (US) | 1999-02-04 | — | — | WO | claimed |
| WO-1998056753-A1 | PREPARATION AND USES OF N-METHYLNITRONE | ALBEMARLE CORPORATION (US) | 1998-12-17 | — | — | WO | claimed |
| US-5760243-A | Preparation and use of 2-methyl-5-phenylisoxazolidine | ALBEMARLE CORPORATION (US) | 1998-06-02 | — | — | US | claimed |
| US-20250084022-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX B.V. (NL) | 2025-03-13 | — | — | US | disclosed |
| US-4910340-A | Catalytic method for preparing symmetrical and nonsymmetrical dialkylhydroxylamines | W. R. GRACE & CO.-CONN. (US) | 1990-03-20 | — | — | US | disclosed |