Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22763532 | 0.93 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1AHRCHRM3MEN1 | |
| SCHEMBL2065340 | 0.90 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1AHRCHRM3MEN1 | |
| SCHEMBL8347844 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1AHRCHRM3MEN1 | |
| SCHEMBL11679867 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1AHRCHRM3ALOX15 | |
| SCHEMBL11683565 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1ALOX15LMNAKDM4E | |
| SCHEMBL8341741 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2L3MBTL1AHRCHRM3MEN1 | |
| SCHEMBL21742085 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1AHRCHRM3ALOX15 | |
| SCHEMBL22420949 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1AHRCHRM3MEN1 | |
| SCHEMBL23364963 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1AHRCHRM3MEN1 | |
| SCHEMBL30471943 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1AHRCHRM3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247575-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2020-12-10 | — | — | WO | disclosed |
| US-5969166-A | RUTHENIUM OR MOLYBDENUM CATALYSTS FOR EPOXIDATION OF ALKENES WITH OXYGEN | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-10-19 | — | — | US | disclosed |