Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | ATP4A | P20648 | 1/20 | 0.37 |
| ▸ | ATP4B | P51164 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288899 | 0.79 | HTR2A (0.51) | HTR2ANR4A2MEN1KMT2AIDO1 | |
| SCHEMBL29555842 | 0.78 | ATM (0.56) | HTR2ANR4A2MEN1KMT2AIDO1 | |
| SCHEMBL12352 | 0.78 | ATM (0.56) | HTR2ANR4A2MEN1KMT2AIDO1 | |
| SCHEMBL14454516 | 0.75 | HTR2A (0.56) | HTR2ANR4A2MEN1KMT2AIDO1 | |
| SCHEMBL21623869 | 0.75 | HTR2A (0.56) | HTR2ANR4A2MEN1KMT2AIDO1 | |
| SCHEMBL8269303 | 0.75 | HTR2A (0.51) | HTR2ANR4A2MEN1KMT2AIDO1 | |
| SCHEMBL8269432 | 0.75 | HTR2A (0.51) | HTR2ANR4A2MEN1KMT2AIDO1 | |
| SCHEMBL8268448 | 0.75 | HTR2A (0.56) | HTR2ANR4A2MEN1KMT2AIDO1 | |
| SCHEMBL20355143 | 0.75 | HTR2A (0.51) | HTR2ANR4A2MEN1KMT2AIDO1 | |
| SCHEMBL26181019 | 0.75 | HTR2A (0.51) | HTR2ANR4A2MEN1KMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004083174-A2 | SULFONYL-AMIDINO CONTAINING AND TETRAHYDROPYRIMIDINO CONTAINING COMPOUNDS AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |