SCHEMBL8342189

SCHEMBL8342189

CN1CCC(Oc2sc(S(=O)(=O)Nc3ccc(C(F)(F)F)c(O[C@@H]4CCN(C)C4)c3)cc2[N+](=O)[O-])C1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 17/20 0.59
FFAR4 Q5NUL3 1/20 0.35
KIF11 P52732 1/20 0.35
TMEM97 Q5BJF2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6822882 0.95 UTS2R (0.55) UTS2R
SCHEMBL6822884 0.95 UTS2R (0.55) UTS2R
SCHEMBL6821322 0.92 UTS2R (0.55) UTS2RTMEM97
SCHEMBL6821330 0.92 UTS2R (0.55) UTS2RTMEM97
SCHEMBL6815857 0.92 UTS2R (0.57) UTS2RFFAR4
SCHEMBL6815846 0.92 UTS2R (0.57) UTS2RFFAR4
SCHEMBL8342604 0.92 UTS2R (0.57) UTS2RFFAR4
SCHEMBL8337332 0.91 UTS2R (0.50) UTS2RTMEM97
SCHEMBL8340971 0.90 UTS2R (0.55) UTS2R
SCHEMBL6817599 0.89 UTS2R (0.60) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043366-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed