SCHEMBL83424

SCHEMBL83424

CC(C)[CH]Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44125 0.74
SCHEMBL6904314 0.70
SCHEMBL27873672 0.70
SCHEMBL27558107 0.70
SCHEMBL10657183 0.70
SCHEMBL1792220 0.70
SCHEMBL2474867 0.70
SCHEMBL7872327 0.67
SCHEMBL501309 0.67
SCHEMBL231877 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 409 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112831063-A Preparation method and application of functionalized cellulose grafted polyacrylic acid composite hydrogel 杭州所予科技有限公司 2021-05-25 CN claimed
CN-104744511-A Fosinopril production method ZHANG YUN 2015-07-01 CN claimed
EP-1697320-B1 A SYNTHETIC METHODOLOGY FOR THE REDUCTIVE ALKYLATION AT THE C-3 POSITION OF INDOLES WYETH LLC (US) 2013-04-10 EP claimed
EP-1892239-B1 Inhibitors of cytosolic phospholipase A2 WYETH LLC (US) 2013-02-20 EP claimed
CN-101104737-B Solidified organic polysiloxanes composition, sealing agent containing the same used for flat panel display and flat panel displaying element SHIN ETSU EHEMICAL CO LTD 2012-07-18 CN claimed
JP-4657605-B2 2011-03-23 JP claimed
US-7906548-B2 Methods for the use of inhibitors of cytosolic phospholipase A2 WYETH LLC (US) 2011-03-15 US claimed
CN-1914170-B Synthetic methodology for the reductive alkylation at the c-3 position of indoles WYETH CORP 2010-07-14 CN claimed
US-7713964-B2 Methods for treating asthmatic conditions WYETH LLC (US) 2010-05-11 US claimed
US-20100113443-A1 LIQUID FORMULATIONS OF PHOSPHOLIPASE ENZYME INHIBITORS WYETH (US) 2010-05-06 US claimed
US-20030166649-A1 Methods for treating arthritic disorders WYETH 2003-09-04 US claimed
US-20030149029-A1 Methods for treating asthmatic conditions WYETH 2003-08-07 US claimed
US-20030144282-A1 Inhibitors of cytosolic phospholipase A2 WYETH 2003-07-31 US claimed
WO-2003048122-A2 INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2 WYETH (US) 2003-06-12 WO claimed
EP-0582790-B1 Novel method of producing 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines AMERICAN CYANAMID CO (US) 1998-12-23 EP claimed
EP-0582790-A1 Novel method of producing 7-(substituted)-9- (substituted glycyl)amido -6-demethyl-6-deoxytetracyclines AMERICAN CYANAMID COMPANY (US) 1994-02-16 EP claimed
US-5284963-A Reacting 9-amino tetracycline derivative with haloacyl halide in mixture of polar aprotic solvent, inert solvent, base; reacting product under inert atmosphere with nucleophilic amine AMERICAN CYANAMID COMPANY (US) 1994-02-08 US claimed
US-5206149-A Reaction of peroxidase, oxidant, luminol and 2-hydroxy-9-fluorenone enhancer; chemiluminescence TORAY INDUSTRIES, INC. (JP) 1993-04-27 US claimed
US-4787929-A POSTEMERGENCE BAYER AKTIENGESELLSCHAFT (DE) 1988-11-29 US claimed
US-4670040-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1987-06-02 US claimed