SCHEMBL8344005

SCHEMBL8344005

CCCCCC#CC(C)=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 5/20 0.52
HMGCR P04035 5/20 0.52
RECQL P46063 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
USP2 O75604 1/20 0.48
ALDH1A1 P00352 1/20 0.48
POLB P06746 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
ALOX12 P18054 1/20 0.48
BLM P54132 1/20 0.48
KMT2A Q03164 1/20 0.48
MCL1 Q07820 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
EPHX2 P34913 4/20 0.42
SELP P16109 1/20 0.40
MMP2 P08253 1/20 0.39
MMP12 P39900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4160194 0.98 PTPN7 (0.55) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL996455 0.93
SCHEMBL29462106 0.83 HMGCR (0.50) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL935043 0.82
SCHEMBL1088244 0.81 PTPN7 (0.57) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL135615 0.80 PTPN7 (0.45) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL2966337 0.79
SCHEMBL23116350 0.79 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL23116298 0.79 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL23116305 0.79 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116096703-A Surfactant and detergent composition 联合利华知识产权控股有限公司 2023-05-09 CN disclosed
CN-113056548-B Detergent composition 联合利华知识产权控股有限公司 2023-05-02 CN disclosed
CN-113015781-B Detergent composition 联合利华知识产权控股有限公司 2022-09-13 CN disclosed
CN-109844083-B Whitening composition 联合利华知识产权控股有限公司 2021-11-09 CN disclosed
CN-110869480-B Whitening composition 联合利华知识产权控股有限公司 2021-08-13 CN disclosed
CN-111479912-B Detergent composition comprising protease 联合利华知识产权控股有限公司 2021-08-10 CN disclosed
CN-113166689-A Detergent composition 联合利华知识产权控股有限公司 2021-07-23 CN disclosed
CN-113056550-A Detergent composition 联合利华知识产权控股有限公司 2021-06-29 CN disclosed
CN-113056549-A Detergent composition 联合利华知识产权控股有限公司 2021-06-29 CN disclosed
CN-113056548-A Detergent composition 联合利华知识产权控股有限公司 2021-06-29 CN disclosed
CN-113015781-A Detergent composition 联合利华知识产权控股有限公司 2021-06-22 CN disclosed
CN-112955531-A Detergent composition 联合利华知识产权控股有限公司 2021-06-11 CN disclosed
CN-112805362-A Detergent composition 联合利华知识产权控股有限公司 2021-05-14 CN disclosed
CN-112739807-A Detergent composition 联合利华知识产权控股有限公司 2021-04-30 CN disclosed
CN-112703246-A Detergent composition 联合利华知识产权控股有限公司 2021-04-23 CN disclosed
CN-108603139-B Whitening composition 荷兰联合利华有限公司 2020-12-04 CN disclosed
CN-107735487-B Laundry detergent compositions 荷兰联合利华有限公司 2020-11-10 CN disclosed
CN-108603140-B Whitening composition 荷兰联合利华有限公司 2020-09-08 CN disclosed
US-5917074-A Preparation and applications of fluorinated propargyl phosphonate reagents UNIVERSITY OF MASSACHUSETTS (US) 1999-06-29 US disclosed
WO-1999018138-A1 PREPARATION AND APPLICATIONS OF FLUORINATED PROPARGYL PHOSPHONATE REAGENTS UNIVERSITY OF MASSACHUSETTS (US) 1999-04-15 WO disclosed