Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204213 | 0.92 | ELANE (0.87) | ELANECYP3A4CYP2C9 | |
| SCHEMBL6232238 | 0.92 | ELANE (0.72) | ELANECYP3A4CYP2C9 | |
| SCHEMBL5205371 | 0.90 | ELANE (0.72) | ELANECYP3A4CYP2C9 | |
| SCHEMBL14498485 | 0.89 | ELANE (0.71) | ELANECYP3A4CYP2C9 | |
| SCHEMBL5204071 | 0.89 | ELANE (0.71) | ELANECYP3A4CYP2C9 | |
| SCHEMBL5205069 | 0.89 | ELANE (0.71) | ELANECYP3A4CYP2C9 | |
| SCHEMBL14889430 | 0.89 | ELANE (0.72) | ELANECYP3A4CYP2C9 | |
| SCHEMBL8344545 | 0.89 | ELANE (0.78) | ELANECYP3A4CYP2C9 | |
| SCHEMBL8342469 | 0.89 | ELANE (0.70) | ELANECYP3A4CYP2C9 | |
| SCHEMBL14498486 | 0.89 | ELANE (0.70) | ELANECYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554246-B1 | DIHYDROPYRIDINONE DERIVATIVES AS HNE INHIBITORS | BAYER HEALTHCARE AG (DE) | 2007-08-22 | — | — | EP | disclosed |
| US-7230017-B2 | Dihydropyridinone derivatives | BAYER HEALTHCARE AG (DE) | 2007-06-12 | — | — | US | disclosed |
| US-7230017-B2 | Dihydropyridinone derivatives | BAYER HEALTHCARE AG (DE) | 2007-06-12 | — | — | US | disclosed |
| WO-2004020410-A2 | DIHYDROPYRIDINONE DERIVATIVES AS HNE INHIBITORS | BAYER HEALTHCARE AG (DE) | 2004-03-11 | — | — | WO | disclosed |