SCHEMBL8344201

SCHEMBL8344201

Oc1c(Cl)cc(OCC=C(F)Cl)cc1Cl

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.35
TTR P02766 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
RECQL P46063 1/20 0.35
THRB P10828 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
CYP2C19 P33261 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8344199 1.00 HSD17B10 (0.35) HSD17B10TTRALDH1A1CYP3A4TSHR
SCHEMBL8341187 0.89 MCL1 (0.33) TSHRCYP1A2CYP2C19SMN1; SMN2HTT
SCHEMBL8341190 0.89 MCL1 (0.33) TSHRCYP1A2CYP2C19SMN1; SMN2HTT
SCHEMBL2166615 0.85 HTT (0.41) HSD17B10TTRALDH1A1CYP3A4TSHR
SCHEMBL8341181 0.84 HSD17B10 (0.34) HSD17B10TTRALDH1A1CYP3A4TSHR
SCHEMBL8341173 0.84 HSD17B10 (0.34) HSD17B10TTRALDH1A1CYP3A4TSHR
SCHEMBL7977624 0.80 HSD17B10 (0.37) HSD17B10TTRALDH1A1CYP3A4TSHR
SCHEMBL8343705 0.78 KDM4E (0.35) ALDH1A1CYP3A4CYP1A2CYP2C9HTT
SCHEMBL8343704 0.78 KDM4E (0.35) ALDH1A1CYP3A4CYP1A2CYP2C9HTT
SCHEMBL8405762 0.78 HTT (0.37) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0787710-B1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 1999-07-28 EP disclosed
US-5869506-A APPLYING TO ACARIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-09 US disclosed
EP-0787710-A1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-06 EP disclosed