Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13917136 | 0.91 | GSK3B (0.63) | GSK3B | |
| SCHEMBL87897 | 0.89 | GSK3B (0.52) | GSK3BCYP2D6 | |
| SCHEMBL8344279 | 0.87 | GSK3B (0.85) | GSK3BCYP2D6 | |
| SCHEMBL8344799 | 0.86 | GSK3B (0.47) | GSK3BCYP2D6 | |
| SCHEMBL8344260 | 0.83 | GSK3B (0.78) | GSK3BCYP2D6 | |
| SCHEMBL1651319 | 0.83 | GSK3B (0.78) | GSK3BCYP2D6 | |
| SCHEMBL13914961 | 0.83 | GSK3B (0.75) | GSK3BCYP2D6 | |
| SCHEMBL13914950 | 0.82 | GSK3B (0.65) | GSK3BCYP2D6 | |
| SCHEMBL8341183 | 0.82 | GSK3B (0.79) | GSK3BCYP2D6 | |
| SCHEMBL8342812 | 0.82 | GSK3B (0.79) | GSK3BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504411-B2 | 2,3,6-Trisubstituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |
| US-7504411-B2 | 2,3,6-Trisubstituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |
| WO-2004085408-A1 | 2, 3, 6-TRISUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2004-10-07 | — | — | WO | disclosed |